Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VCP P55072 valosin containing protein 1.00 0.469 0.923
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SYNCRIP O60506 synaptotagmin binding cytoplasmic RNA interacting protein Nucleic acid binding 1.00 0.722 0.269
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
PSAP P07602 prosaposin 0.99 0.532 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PFN1 P07737 profilin 1 0.73 0.565 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NEFL P07196 neurofilament light 0.488 0.769
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
CST3 P01034 cystatin C 3.9E-03 0.436 0.808